Polymerator is a program that aids the interpretation of tandem mass spectrometry (MS/MS) data from synthetic
The software is particularly focused toward aiding the end-group determination of these materials by
significantly speeding up
the interpretation process. This allows information on the initiator and/or chain transfer agents, used to
generate the polymer,
and the mechanism of termination to be inferred from the data much more rapidly. The software allows the
validity of hypothesized
structures to be rapidly tested by automatically annotating the data file using previously proposed
fragmentation rules for synthetic
This program is freely distributed. Use at your own risk.
Java Runtime Environment v1.4.2 or later.
Once downloaded extract the zip file and then double click on the Polymerator-v1.2.jar
file in order to start the program.
The program has been described in the following publication. Please reference if you
use the program in your own work.
Thalassinos, K., Jackson, A. T., Williams, J. P., Hilton, G. R., Slade, S. E. and Scrivens, J. H.
(2007). Novel software for the assignment of peaks from tandem mass spectrometry spectra of synthetic polymers.
Journal of the American Society for Mass Spectrometry
Other publications where polymerator has been used are:
Jackson, A. T., Slade, S. E., Thalassinos, K. and Scrivens, J. H. (2008). End group characterisation of
poly(propylene glycol)s by means of electrospray ionisation-tandem mass spectrometry (ESI-MS/MS).
Analytical and Bioanalytical Chemistry
Williams, J. P., Hilton, G. R., Thalassinos, K., Jackson, A. T. and Scrivens, J. H. (2007). The rapid
characterisation of poly(ethylene glycol) oligomers using desorption electrospray ionisation tandem mass
spectrometry combined with novel product ion peak assignment software.
Rapid Communications in Mass Spectrometry