Structural Mass Spectrometry and Protein Misfolding

Our Lab Studies The Structure And Dynamics Of Proteins And Protein Complexes Using A Combination Of Structural Mass Spectrometry Approaches Such As, Native, Ion Mobility And Crosslinking. We Also Develop Computational Tools To Process The Data Obtained. 


Recent news and developments from the lab.


Genomic investigations of unexplained acute hepatitis in children

Since its first identification in Scotland, over 1,000 cases of unexplained paediatric hepatitis in children have been reported worldwide, including 278 cases in the UK1. Here we report an investigation of 38 cases, 66 age-matched immunocompetent controls and 21 immunocompromised comparator participants, using a combination of genomic, transcriptomic, proteomic and immunohistochemical methods. 

Article in Nature

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