Our lab is interested in studying the structure and dynamics of proteins and protein complexes using a combination of structural mass spectrometry approaches such as, native, ion mobility and crosslinking. We also develop computational tools to process the data obtained. Current research projects involve developing methods for the study of flexible proteins, the study of protein complexes of type IV secretion systems, protein misfolding diseases such as alpha-1 antitrypsin.
June 2019: New publication in Analytical Chemistry showing that a cyclic ion mobility instrument is compatible with protein native MS analyses
January 2019: New publication in Analytical Chemistry showing a method for the analysis of crosslinked peptides using a QTOF
May 2018: New publication in Structure on using cross-linking to model protein complexes
May 2018: Abu joins the lab
January 2018: New publication in IJMS describing the use of Genetic Algorithms to deconvolute collision induced unfolding ion mobility data
November 2017: Tanya successfully defends her PhD!
September 2017: New publication in JACS
January 2017: New Website built using Zurb Foundation
October 2016: Charlie joins the lab