PhD Student
Phone: +44 (0)20 7679 3836
Email: elnaz.jamili.12@ucl.ac.uk
Address
Department of Chemical Engineering
University College London
Torrington Place
London WC1E 7JE
United Kingdom
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PhD Student Phone: +44 (0)20 7679 3836 Email: elnaz.jamili.12@ucl.ac.uk |
Address |
Education
Awards
Bio
Elnaz received her degree as a Master of Engineering (MEng) from the University of Birmingham in 2012. Just after her graduation, she started a PhD in Chemical Engineering at University College London in November of 2012. Her research work is focused on optimal control of gene delivery.
Research Project
Model-based optimal control of non-viral gene delivery.
Gene therapy has great potential in becoming a viable tool for the effective treatment of diseases. For effective gene therapy a gene delivery system has to balance between the two main objectives: high efficacy and low toxicity. However, these two objectives usually conflict with each other, i.e. one objective can not be improved upon without sacrificing the other. In this work, a methodology for systematic and quantitative analysis of these conflicting objectives will be developed to help evaluate translation of developments in the area of gene therapy into clinical practice. This will be achieved by using the mathematical models from literature and amending them for optimal control purposes. Issues pertaining to presence of constraints in the model will also be addressed.
Research Group
Product and process systems engineering