Prof Paul A. Dalby
Department of Biochemical Engineering, University College London
Paul Dalby is a Professor in Biochemical
Engineering and Biotechnology at University
College London, where he has been a principle investigator since April
2000. His protein engineering research has a distinctly bioprocess flavour
which aims to address key challenges in rapid industrial process and protein formulation development,
using a combination of novel automated microscale and microfluidic methods, biophysics, and molecular dynamics simulations,
as well as employing directed evolution and bioinformatics to improve the
process performance of biocatalytic enzymes and biopharmaceuticals..
He graduated with a Natural Sciences degree from the University of Cambridge and received his PhD in 1998, also from the University of Cambridge, for work on protein engineering and protein folding under the guidance of Sir Prof Alan Fersht. He then undertook a Postdoctoral research fellowship at the University of Pennsylvania in the laboratory of Prof William DeGrado in collaboration with Ron Hoess at DuPont (Wilmington, Del.), to engineer WW domain proteins using phage display techniques.
Since July 2008 Paul has been Chair of the Royal Society of Chemistry's Biotechnology Subject Group which aims to engage academia, industry and the public in debate and scientific discussion on advances in Biotechnology. He received the Evonik European Science-to-Business Award in November 2008 for his work on engineering enzyme routes for the production of chiral intermediates.
He is Co-Director of the EPSRC Future Targeted Healthcare Manufacturing Hub and Director of the EPSRC Centre for Doctoral Training (CDT) in Emergent Macromolecular Therapies.