G. Weitsman, J. N. E. Chan, J. Nedbal, P. R. Barber, A. Volgina, C. Stevens, S. Poland, S. Ameer-Beg, K. Suhling, J. Rios-Doria, and T. Ng, Small molecule PD-L1 inhibitor modulates expression of PD-L1 on the cell surface - a potential mechanism of blocking interaction with PD-1, European Journal of Cancer 174, S70 (2022).

J. M. Vicencio, R. Evans, R. Green, Z. An, J. Deng, C. Treacy, R. Mustapha, J. Monypenny, C. Costoya, K. Lawler, K. Ng, K. De-Souza, O. Coban, V. Gomez, J. Clancy, S. H. Chen, A. Chalk, F. Wong, P. Gordon, C. Savage, C. Gomes, T. Pan, G. Alfano, L. Dolcetti, J. N. E. Chan, F. Flores-Borja, P. R. Barber, G. Weitsman, D. Sosnowska, E. Capone, S. Iacobelli, D. Hochhauser, J. A. Hartley, M. Parsons, J. N. Arnold, S. Ameer-Beg, S. A. Quezada, Y. Yarden, G. Sala, and T. Ng, Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans, Cell Death Dis 13, 1-14 (2022).

D. J. Propper, F. Gao, M. P. Saunders, D. Sarker, J. A. Hartley, V. J. Spanswick, H. L. Lowe, L. D. Hackett, T. T. Ng, P. R. Barber, G. E. Weitsman, S. Pearce, L. White, A. Lopes, S. Forsyth, and D. Hochhauser, PANTHER: AZD8931, inhibitor of EGFR, ERBB2 and ERBB3 signalling, combined with FOLFIRI: a Phase I/II study to determine the importance of schedule and activity in colorectal cancer, Br J Cancer 1-10 (2022).

A. Hertweck, M. Vila de Mucha, P. R. Barber, R. Dagil, H. Porter, A. Ramos, G. M. Lord, and R. G. Jenner, The TH1 cell lineage-determining transcription factor T-bet suppresses TH2 gene expression by redistributing GATA3 away from TH2 genes, Nucleic Acids Research gkac258 (2022).

V. Gomez, M. Galazi, G. Weitsman, J. Monypenny, F. Al-Salemee, P. R. Barber, K. Ng, R. Beatson, B. Szokol, and L. Orfi, HER2 mediates PSMA/mGluR1-driven resistance to the DS-7423 dual PI3K/mTOR inhibitor in PTEN wild-type prostate cancer models, Molecular cancer therapeutics 21, 667-676 (2022).

P. R. Barber, R. Mustapha, F. Flores-Borja, G. Alfano, K. Ng, G. Weitsman, L. Dolcetti, A. A. Mohamed, F. Wong, J. M. Vicencio, M. Galazi, J. W. Opzoomer, J. N. Arnold, S. Thavaraj, S. Kordasti, J. Doyle, J. Greenberg, M. T. Dillon, K. J. Harrington, M. Forster, A. C. Coolen, and T. Ng, Predicting progression-free survival after systemic therapy in advanced head and neck cancer: Bayesian regression and model development, eLife 11, e73288 (2022).

J. W. Opzoomer, J. A. Timms, K. Blighe, T. P. Mourikis, N. Chapuis, R. Bekoe, S. Kareemaghay, P. Nocerino, B. Apollonio, A. G. Ramsay, M. Tavassoli, C. Harrison, F. Ciccarelli, P. Parker, M. Fontenay, P. R. Barber, J. N. Arnold, and S. Kordasti, ImmunoCluster provides a computational framework for the nonspecialist to profile high-dimensional cytometry data, eLife 10, e62915 (2021).

S. Abdul-Jawad, L. Bau, T. Alaguthurai, I. del Molino del Barrio, A. G. Laing, T. S. Hayday, L. Monin, M. Munoz-Ruiz, L. McDonald, I. Francos Quijorna, D. McKenzie, R. Davis, A. Lorenc, J. N. E. Chan, S. Ryan, E. Bugallo-Blanco, R. Yorke, S. Kamdar, M. Fish, I. Zlatareva, P. Vantourout, A. Jennings, S. Gee, K. Doores, K. Bailey, S. Hazell, J. De Naurois, C. Moss, B. Russell, A. A. Khan, M. Rowley, R. Benjamin, D. Enting, D. Alrifai, Y. Wu, Y. Zhou, P. Barber, T. Ng, J. Spicer, M. Van Hemelrijck, M. Kumar, J. Vidler, Y. Lwin, P. Fields, S. N. Karagiannis, A. C. C. Coolen, A. Rigg, S. Papa, A. C. Hayday, P. E. M. Patten, and S. Irshad, Acute Immune Signatures and Their Legacies in Severe Acute Respiratory Syndrome Coronavirus-2 Infected Cancer Patients, Cancer Cell 39, 257-275.e6 (2021).

B. T. Li, F. Michelini, S. Misale, E. Cocco, L. Baldino, Y. Cai, S. Shifman, H.-Y. Tu, M. L. Myers, C. Xu, M. Mattar, I. Khodos, M. Little, B. Qeriqi, G. Weitsman, C. J. Wilhelm, A. S. Lalani, I. Diala, R. A. Freedman, N. U. Lin, D. B. Solit, M. F. Berger, P. R. Barber, T. Ng, M. Offin, J. M. Isbell, D. R. Jones, H. A. Yu, S. Thyparambil, W.-L. Liao, A. Bhalkikar, F. Cecchi, D. M. Hyman, J. S. Lewis, D. J. Buonocore, A. L. Ho, V. Makker, J. S. Reis-Filho, P. Razavi, M. E. Arcila, M. G. Kris, J. T. Poirier, R. Shen, J. Tsurutani, G. A. Ulaner, E. de Stanchina, N. Rosen, C. M. Rudin, and M. Scaltriti, HER2-mediated internalization of cytotoxic agents in ERBB2 amplified or mutant lung cancers, Cancer Discov (2020).

J. A. Levitt, S. P. Poland, N. Krstajic, K. Pfisterer, A. Erdogan, P. R. Barber, M. Parsons, R. K. Henderson, and S. M. Ameer-Beg, Quantitative real-time imaging of intracellular FRET biosensor dynamics using rapid multi-beam confocal FLIM, Scientific Reports 10, 1-9 (2020).

V. Gomez, T. R. Eykyn, R. Mustapha, F. Flores-Borja, V. Male, P. R. Barber, A. Patsialou, R. Green, F. Panagaki, C. W. Li, G. O. Fruhwirth, S. Ros, K. M. Brindle, and T. Ng, Breast cancer-associated macrophages promote tumorigenesis by suppressing succinate dehydrogenase in tumor cells, Sci. Signal. 13, (2020).

D. Gao, P. R. Barber, J. V. Chacko, M. A. K. Sagar, C. T. Rueden, A. R. Grislis, M. C. Hiner, and K. W. Eliceiri, FLIMJ: An open-source ImageJ toolkit for fluorescence lifetime image data analysis, PLOS ONE 15, e0238327 (2020).

P. R. Barber, G. Weitsman, K. Lawler, J. Barrett, M. Rowley, M. Rodriguez-Justo, D. Fisher, F. Gao, I. D. C. Tullis, J. Deng, L. Brown, R. Kaplan, D. Hochhauser, R. Adams, T. Maughan, B. Vojnovic, A. C. C. Coolen, and T. Ng, HER2-HER3 heterodimer quantification by FRET-FLIM and patient subclass analysis of the COIN colorectal trial, J Natl Cancer Inst djz231 (2020).

A. N. Singh, J. Oehler, I. Torrecilla, S. Kilgas, S. Li, B. Vaz, C. Guerillon, J. Fielden, E. Hernandez-Carralero, E. Cabrera, I. D. Tullis, M. Meerang, P. R. Barber, R. Freire, J. Parsons, B. Vojnovic, A. E. Kiltie, N. Mailand, and K. Ramadan, The p97-Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8, The EMBO Journal 0, e102361 (2019).

R. Evans, F. Flores-Borja, S. Nassiri, E. Miranda, K. Lawler, A. Grigoriadis, J. Monypenny, C. Gillet, J. Owen, P. Gordon, V. Male, A. Cheung, F. Noor, P. Barber, R. Marlow, E. Francesch-Domenech, G. Fruhwirth, M. Squadrito, B. Vojnovic, A. Tutt, F. Festy, M. De Palma, and T. Ng, Integrin-Mediated Macrophage Adhesion Promotes Lymphovascular Dissemination in Breast Cancer, Cell Reports 27, 1967-1978.e4 (2019).

J. Monypenny, H. Milewicz, F. Flores-Borja, G. Weitsman, A. Cheung, R. Chowdhury, T. Burgoyne, A. Arulappu, K. Lawler, P. R. Barber, J. M. Vicencio, M. Keppler, W. Wulaningsih, S. M. Davidson, F. Fraternali, N. Woodman, M. Turmaine, C. Gillett, D. Franz, S. A. Quezada, C. E. Futter, A. V. Kriegsheim, W. Kolch, B. Vojnovic, J. G. Carlton, and T. Ng, ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation, Cell Reports 24, 630-641 (2018).

T. Ng, F. Flores-Borja, G. Alfano, P. Barber, G. Weitsman, F. Wong, J. Vicencio, M. Galazi, J. Doyle, J. Greenberg, M. D. Forster, and A. Coolen, The use of exosome and immune profiling to analyze a phase 2 study on the addition of patritumab or placebo to cetuximab and a platinum agent for recurrent / metastatic head and neck cancer (R/M HNSCC) patients., JCO 36, 6043-6043 (2018).

J. Claus, G. Patel, F. Autore, A. Colomba, G. Weitsman, T. N. Soliman, S. Roberts, L. C. Zanetti-Domingues, M. Hirsch, F. Collu, R. George, E. Ortiz-Zapater, P. R. Barber, B. Vojnovic, Y. Yarden, M. L. Martin-Fernandez, A. Cameron, F. Fraternali, T. Ng, and P. J. Parker, Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface, eLife Sciences 7, e32271 (2018).

D. Volpi, I. D. C. Tullis, P. R. Barber, E. M. Augustyniak, S. C. Smart, K. A. Vallis, and B. Vojnovic, Electrically tunable fluidic lens imaging system for laparoscopic fluorescence-guided surgery, Biomed. Opt. Express, BOE 8, 3232-3247 (2017).

G. Weitsman, N. J. Mitchell, R. Evans, A. Cheung, T. L. Kalber, R. Bofinger, G. O. Fruhwirth, M. Keppler, Z. V. F. Wright, P. R. Barber, P. Gordon, T. de Koning, W. Wulaningsih, K. Sander, B. Vojnovic, S. Ameer-Beg, M. Lythgoe, J. N. Arnold, E. Årstad, F. Festy, H. C. Hailes, A. B. Tabor, and T. Ng, Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor, Oncogene (2017). DIO: 10.1038/onc.2016.522.

S. Irshad, F. Flores-Borja, K. Lawler, J. Monypenny, R. Evans, V. Male, P. Gordon, A. Cheung, P. Gazinska, F. Noor, F. Wong, A. Grigoriadis, G. O. Fruhwirth, P. R. Barber, N. Woodman, D. Patel, M. Rodriguez-Justo, J. Owen, S. G. Martin, S. E. Pinder, C. E. Gillett, S. P. Poland, S. Ameer-Beg, F. McCaughan, L. M. Carlin, U. Hasan, D. R. Withers, P. Lane, B. Vojnovic, S. A. Quezada, P. Ellis, A. N. J. Tutt, and T. Ng, RORγt+ Innate Lymphoid Cells Promote Lymph Node Metastasis of Breast Cancers, Cancer Research 77, 1083-1096 (2017).

A. Bosch-Vilaró, B. Jacobs, V. Pomella, L. Abbasi Asbagh, R. Kirkland, J. Michel, S. Singh, X. Liu, P. Kim, G. Weitsman, P. R. Barber, B. Vojnovic, T. Ng, and S. Tejpar, Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells, Oncotarget 8, 4277-4288 (2017).

G. Weitsman*, P. R. Barber*, L. K. Nguyen*, K. Lawler, G. Patel, N. Woodman, M. T. Kelleher, S. E. Pinder, M. Rowley, P. A. Ellis, A. D. Purushotham, A. C. Coolen, B. N. Kholodenko, B. Vojnovic, C. Gillett and T. Ng, HER2-HER3 dimer quantification by FLIM-FRET predicts breast cancer metastatic relapse independently of HER2 IHC status, Oncotarget 7(32), 51012-51026 (2016).

M. I. Rowley, A. C. C. Coolen, B. Vojnovic, and P. R. Barber, Robust Bayesian Fluorescence Lifetime Estimation, Decay Model Selection and Instrument Response Determination for Low-Intensity FLIM Imaging, PLOS ONE 11(6), e0158404 (2016).

T. Puri, A. Chalkidou, R. Henley-Smith, A. Roy, P. R. Barber, T. Guerrero-Urbano, R. Oakley, R. Simo, J.-P. Jeannon, M. McGurk, E. W. Odell, M. J. O'Doherty, and P. K. Marsden, A method for accurate spatial registration of PET images and histopathology slices, EJNMMI Research 5, 64 (2015).

S. P. Poland, N. Krstajic, J. Monypenny, S. Coelho, D. Tyndall, R. J. Walker, V. Devauges, J. Richardson, N. Dutton, P. Barber, D. D.-U. Li, K. Suhling, T. Ng, R. K. Henderson, and S. M. Ameer-Beg, A high speed multifocal multiphoton fluorescence lifetime imaging microscope for live-cell FRET imaging, Biomed. Opt. Express 6, 277-296 (2015).

O. Coban, L. C. Zanetti-Dominguez, D. R. Matthews, D. J. Rolfe, G. Weitsman, P. R. Barber, J. Barbeau, V. Devauges, F. Kampmeier, M. Winn, B. Vojnovic, P. J. Parker, K. A. Lidke, D. S. Lidke, S. M. Ameer-Beg, M. L. Martin-Fernandez, and T. Ng, Effect of Phosphorylation on EGFR Dimer Stability Probed by Single-Molecule Dynamics and FRET/FLIM, Biophysical Journal 108, 1013-1026 (2015).

J. J. Tao, P. Castel, N. Radosevic-Robin, M. Elkabets, N. Auricchio, N. Aceto, G. Weitsman, P. Barber, B. Vojnovic, H. Ellis, N. Morse, N. T. Viola-Villegas, A. Bosch, D. Juric, S. Hazra, S. Singh, P. Kim, A. Bergamaschi, S. Maheswaran, T. Ng, F. Penault-Llorca, J. S. Lewis, L. A. Carey, C. M. Perou, J. Baselga, and M. Scaltriti, Antagonism of EGFR and HER3 Enhances the Response to Inhibitors of the PI3K-Akt Pathway in Triple-Negative Breast Cancer, Sci. Signal. 7, ra29 (2014).

G. Weitsman, K. Lawler, M. T. Kelleher, J. E. Barrett, P. R. Barber, E. Shamil, F. Festy, G. Patel, G. O. Fruhwirth, L. Huang, I. D. C. Tullis, N. Woodman, E. Ofo, S. M. Ameer-Beg, S. Irshad, J. Condeelis, C. E. Gillett, P. A. Ellis, B. Vojnovic, A. C. C. Coolen, and T. Ng, "Imaging tumour heterogeneity of the consequences of a PKCa-substrate interaction in breast cancer patients," Biochemical Society Transactions 42, 1498-1505 (2014).

P. R. Barber, I. D. C. Tullis, M. I. Rowley, C. D. Martins, G. Weitsman, K. Lawler, M. Coffey, N. Woodman, C. E. Gillett, T. Ng, and B. Vojnovic, The Gray Institute open microscopes applied to radiobiology and protein interaction studies, Proc. SPIE 8949, 89490D-89490D-17 (2014).

P.A. Young, A. Grislis, P.R. Barber, P.J. Keely, K.W. Eliceiri. Data Processing for Time-Domain Fluorescence Lifetime Imaging Microscopy. Microscopy and Microanalysis 19: 758-759 doi:10.1017/S1431927613005783 (2013).

P. R. Barber, I. D. C. Tullis, G. P. Pierce, R. G. Newman, J. Prentice, M. I. Rowley, D. R. Matthews, S. M. Ameer-Beg, and B. Vojnovic. The Gray Institute 'Open' High-content, Fluorescence Lifetime Microscopes. J. Microscopy. doi:10.1111/jmi.12057 (2013). Supporting Information

J. C. G. Jeynes, M. J. Merchant, L. Barazzuol, M. Barry, D. Guest, V. V. Palitsin, G. W. Grime, I. D. C. Tullis, P. R. Barber, B. Vojnovic, and K. J. Kirkby, "Broadbeam" irradiation of mammalian cells using a vertical microbeam facility, Radiat Environ Biophys 52, 513-521 (2013).

S. Akerman, M. Fisher, R. A. Daniel, D. Lefley, C. C. Reyes-Aldasoro, S. J. Lunt, S. Harris, M. Bjorndahl, L. J. Williams, H. Evans, P. R. Barber, B. Vojnovic, C. Kanthou, G. M. Tozer, Influence of Soluble or Matrix-bound Isoforms of Vascular Endothelial Growth factor-A on Tumor Response to Vascular-targeted Strategies. Int. J. Cancer. doi:10.1002/ijc.28281 (2013).

M. J. Merchant, J. C. G. Jeynes, G. W. Grime, V. Palitsin, I. D. C. Tullis, P. R. Barber, B. Vojnovic, R. P. Webb, and K. J. Kirkby, A focused scanning vertical beam for charged particle irradiation of living cells with single counted particles. Radiation Research 178, 182-190 (2012).

H. C. Mandeville, Q. S. Ng, F. M. Daley, P. R. Barber, G. Pierce, J. Finch, M. Burke, Mb. Bell, E. R. Townsend, R. Kozarski, B. Vojnovic, P. J. Hoskin, and V. Goh, Operable Non-Small Cell Lung Cancer: Correlation of Volumetric Helical Dynamic Contrast-Enhanced CT Parameters with Immunohistochemical Markers of Tumor Hypoxia. Radiology (2012).

D. R. Matthews, G. O. Fruhwirth, G. Weitsman, L. M. Carlin, E. Ofo, M. Keppler, P. R. Barber, I. D. C. Tullis, B. Vojnovic, T. Ng, and S. M. Ameer-Beg, A Multi-Functional Imaging Approach to High-Content Protein Interaction Screening, PLoS ONE 7, e33231 (2012).

K. Rothkamm, J. C. Crosbie, F. Daley, S. Bourne, P. R. Barber, B. Vojnovic, L. Cann, and P. A. W. Rogers, In situ Biological Dose Mapping Estimates the Radiation Burden Delivered to "Spared" Tissue between Synchrotron X-Ray Microbeam Radiotherapy Tracks, PLoS ONE 7, e29853 (2012).

M. Baker, S. D. Robinson, T. Lechertier, P. R. Barber, B. Tavora, G. D'Amico, D. T. Jones, B. Vojnovic, and K. Hodivala-Dilke, Use of the mouse aortic ring assay to study angiogenesis, Nat. Protocols 7, 89-104 (2012).

L. M. Carlin, R. Evans, H. Milewicz, L. Fernandes, D. R. Matthews, M. Perani, J. Levitt, M. D. Keppler, J. Monypenny, T. Coolen, P. R. Barber, B. Vojnovic, K. Suhling, F. Fraternali, S. Ameer-Beg, P. J. Parker, N. S. B. Thomas, and T. Ng, A Targeted siRNA Screen Identifies Regulators of Cdc42 Activity at the Natural Killer Cell Immunological Synapse, Sci. Signal. 4, ra81 (2011).

S. E. Rademakers, P. F. Rijken, W. J. Peeters, M. M. Nijkamp, P. R. Barber, J. Laak, A. J. Kogel, J. Bussink, and J. H. Kaanders, Parametric mapping of immunohistochemically stained tissue sections; a method to quantify the colocalization of tumor markers, Cellular Oncology 34, 119-129 (2011).

I. A. Pope, P. R. Barber, S. Horn, E. Ainsbury, K. Rothkamm, and B. Vojnovic, A portable microfluidic fluorescence spectrometer device for [gamma]-H2AX-based biological dosimetry, Radiation Measurements 46, 907-911 (2011).

B. Cornelissen, S. Darbar, R. Hernandez, V. Kersemans, I. Tullis, P. R. Barber, S. Smart, B. Vojnovic, R. Reilly, and K. A. Vallis, ErbB-2 Blockade and Prenyltransferase Inhibition Alter Epidermal Growth Factor and Epidermal Growth Factor Receptor Trafficking and Enhance 111In-DTPA-hEGF Auger Electron Radiation Therapy, Journal of Nuclear Medicine 52, 776 -783 (2011).

G. S. Patel, T. Kiuchi, K. Lawler, E. Ofo, G. O. Fruhwirth, M. Kelleher, E. Shamil, R. Zhang, P. R. Selvin, G. Santis, J. Spicer, N. Woodman, C. E. Gillett, P. R. Barber, B. Vojnovic, G. Keri, T. Schaeffter, V. Goh, M. J. O'Doherty, P. A. Ellis, and T. Ng, The challenges of integrating molecular imaging into the optimization of cancer therapy, Integr. Biol. (2011).

Fruhwirth G. O., et al., How Forster Resonance Energy Transfer Imaging Improves the Understanding of Protein Interaction Networks in Cancer Biology. ChemPhysChem, 2011. 12, 442-461.

Rowley M., et al., Bayesian analysis of Fluorescence lifetime imaging data. Proc SPIE, 2011. 7903, p. 74

Barber P.R., et al., A Bayesian method for single molecule, fluorescence burst analysis. Biomed. Opt. Express, 2010 1, p. 1148-1158.

Matthews D.R., et al., Time-lapse FRET microscopy using fluorescence anisotropy, Journal of Microscopy, 2010 237, p. 51-62.

Makrogianneli, K., et al., Integrating Receptor Signal Inputs That Influence Small Rho GTPase Activation Dynamics at the Immunological Synapse. Mol. Cell. Biol., 2009. 29(11): p. 2997-3006.

Barber, P.R., et al., Multiphoton time-domain FLIM: Practical application to protein-protein interactions using global analysis. J R Soc Interface, 2009. 6: p. S93-S105.

Kelleher, M., et al., The potential of optical proteomic technologies to individualize prognosis and guide rational treatment for cancer patients. Targeted Oncology 4, 235-252 (2009).

Badie, S., et al., RAD51C facilitates checkpoint signaling by promoting CHK2 phosphorylation. J. Cell Biol., 2009. 185(4): p. 587-600.

Vojnovic, B., et al., Detecting Objects, WIPO, Patent:PCT/GB2008/000216, 2008.

Tozer, G.M., et al., Blood Vessel Maturation and Response to Vascular-Disrupting Therapy in Single Vascular Endothelial Growth Factor-A Isoform-Producing Tumors. Cancer Res, 2008. 68(7): p. 2301-2311.

Matthews, D.R., et al., A high-content screening platform utilizing polarization anisotropy and FLIM microscopy. Proc. SPIE, 2008. 6859.

Levitt, J.A., et al., Multidimensional multiphoton fluorescence lifetime imaging of cells. Proc. SPIE, 2008. 6860.

Errington, R.J., et al. Detection Of Gamma-H2ax Foci Using High Content Screening Formats. in ISAC XXIV. 2008. Budapest, Hungary.

Barber, P.R., et al. Towards high-throughput FLIM for protein-protein interaction screening of live cells and tissue microarrays. in 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI '08). 2008.

Reyes-Aldasoro, C.C., et al., Estimation of Apparent Tumor Vascular Permeability from Multiphoton Fluorescence Microscopic Images of P22 Rat Sarcomas In Vivo. Microcirculation, 2007. 15(1): p. 65-79.

Prag, S., et al., Activated Ezrin Promotes Cell Migration through Recruitment of the GEF Dbl to Lipid Rafts and Preferential Downstream Activation of Cdc42. Mol. Biol. Cell, 2007. 18(8): p. 2935-2948.

Pope, I.A., et al., A complete, self-contained, optical biochip with live-cell imaging capability, in SPIE Photonics West. 2007, SPIE: San Jose, USA.

McConnell, G., et al., Time-correlated single-photon counting fluorescence lifetime confocal imaging of decayed and sound dental structures with a white-light supercontinuum source. Journal of Microscopy, 2007. 225(2): p. 126-136.

Matthews, D.R., et al., A fluorescence biochip with a plasmon active surface. Proc. SPIE, 2007. 6450.

Everett, S.A., et al. Cytochrome P450 CYP1B1 over-expression in malignant melanoma and disseminated disease: identification of a key indication for the enzyme/prodrug therapy of cancer. in AACR Annual Meeting 2007. 2007. Los Angeles, California, USA.

Everett, S.A., et al., Profiling cytochrome P450 CYP1 enzyme expression in primary melanoma and disseminated disease utilizing spectral imaging microscopy (SIM). J Clin Oncol (Meeting Abstracts), 2007. 25(18_suppl): p. 8556-.

Barber, P.R., et al., Gamma-H2AX Foci Counting: Image processing and control software for high-content screening. Proc. SPIE, 2007. 6441: p. 64411M.

Tullis, I.D.C., et al., Mapping femtosecond pulse front distortion and group velocity dispersion in multiphoton microscopy. Proc. SPIE, 2006. 6089: p. 158-164.

Reyes-Aldasoro, C.C., et al., Multiphoton fluorescence microscopy for assessing vascular permeability in experimental tumours; effects of CA-4-P, VEGF isoforms & ANG-1. Angiogenesis, 2006. 9(1): p. 26.

Matthews, D.R., et al., Technique for measurement of fluorescence lifetime by use of stroboscopic excitation and continuous-wave detection. Applied Optics, 2006. 45: p. 2115-2123.

Lucas, L.A.G., et al., Effect Of Angiostatin4.5 On Tumour Blood Vessels. Angiogenesis, 2006. 9(1): p. 38.

Barber, P.R., et al., The GCI Multitarget X-ray Microprobe: Imaging, Control and Software Automation. Extended Abstracts of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response published in Radiation Research, 2006. 166: p. 663-4.

Akerman, S., et al., Tumour Cells Expressing Only Single Vegf Isoforms (120, 164 Or 188) Form Tumours With Very Different Vascular Maturities And Response To Combretastatin A-4-P. Angiogenesis, 2006. 9(1): p. 28.

Tozer, G.M., et al. Tumour susceptibility to the vascular disrupting agent, combretastatin A-4-P, is modified by differential expression of individual isoforms of VEGF-A. in Tumour Microenvironment. 2005. Oxford.

Tozer, G.M., et al. The influence of different isoforms of vascular endothelial growth factor A (VEGF-A) on tumor vascular maturation and response to the vascular disrupting agent, combretastatin A-4 phosphate. in 96th AACR Annual Meeting. 2005. Anaheim CA.

Tozer, G.M., et al., Intravital imaging of tumour vascular networks using multi-photon fluorescence microscopy. Advanced Drug Delivery Reviews, 2005. 57(1): p. 135-152.

Rankov, V., et al., An algorithm for image stitching and blending. Proc. SPIE, 2005. 5701: p. 190-199.

Parsons, M., et al., Spatially Distinct Binding of Cdc42 to PAK1 and N-WASP in Breast Carcinoma Cells. Molecular and Cellular Biology, 2005. 25(5): p. 1680-1695.

Lucas, L.A.G., et al., Molecular targeting of angiogenesis - an intravital imaging study, in NCRI. 2005: Birmingham, UK.

Lucas, L., et al., Combretastatin a-4-p treatment reduces red blood cell velocity in tumour microvessels in a time and dose dependent manner, in Cancer RRG Northern Ireland - annual retreat. 2005: Antrim, Northern Ireland.

Barber, P.R., R.J. Edens, and B. Vojnovic, Acquisition and analysis of spectral image data by linear un-mixing, cluster computing and a novel spectral imager. Proc. SPIE, 2005. 5694: p. 53-61.

Barber, P.R., et al., Global and pixel kinetic data analysis for FRET detection by multi-photon time-domain FLIM. Proc. SPIE, 2005. 5700: p. 171-181.

Barber, P.R. Image Processing and Analysis in 2D and 3D Microscopy. in Optoelectronics for Use in the Diagnosis of Cancer. 2005. Grasmere, Cumbria, UK: The Rank Prize Funds.

Barber, P.R. Multiphoton and Spectral imaging in Cancer Research. in Lecture to MRes students. 2005. King's College London, The Strand, London, UK.

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